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Granzymes initiate GSDMBNT‐ and GSDMENT‐induced pyroptosis. GzmA or GzmB, which is released from killer cytotoxic lymphocytes, induces GSDMB‐ or GSDME‐dependent pyroptosis in tumor cells, respectively. GzmA, granzyme A; GzmB, granzyme B; NK cells, natural killer cells.
