Table I.
Group | 0 weeks | 2 weeks | 4 weeks | 6 weeks | 8 weeks |
---|---|---|---|---|---|
Control | 239.00±11.00 | 265.50±14.32 | 277.83±15.03 | 304.67±30.53 | 321.33±33.42 |
DR | 240.17±10.11a | 218.00±18.35a | 208.33±18.27a | 194.67±17.65a | 180.50±15.08a |
DR + BBR-L | 237.83±9.00 | 217.50±15.60 | 204.83±15.22 | 188.50±10.37 | 173.83±16.12 |
DR + BBR-H | 239.33±10.88 | 222.33±19.01 | 207.33±17.84 | 192.00±17.37 | 178.17±20.00 |
P<0.0001 vs. control. DR, diabetic retinopathy; BBR, berberine; BBR-L, 100 mg/kg BBR; BBR-H, 200 mg/kg BBR.