. 2020 Sep 17;22(5):4151–4162. doi: 10.3892/mmr.2020.11521

Table III.

Myocardial content of genes in CON (n=8), DOX (n=12) and DOX+Val (n=12) groups.

Protein, ng/ml	CON (mean ± SD)	DOX (mean ± SD)	DOX+Val (mean ± SD)
Renin	27.27±2.32	41.82±3.76^a	34.02±3.14^a,b
ALD	246.55±68.03	376.87±85.34^a	264.25±71.05^b
MDA	2.55±0.72	3.99±0.93^a	2.72±0.77^b
SOD	144.61±32.15	105.48±22.65^a	138.84±18.16^b
ROS	275.42±71.86	355.64±100.17^a	327.41±69.88^b
TNF-α	173.52±20.88	260.24±23.47^a	211.77±20.59^b
IL-6	77.09±17.26	88.28±21.73^a	73.27±15.15^b
BNP	208.31±33.62	331.77±22.45^a	275.73±26.21^a,b
NOX1	59.77±8.94	68.87±10.16^a	59.13±7.65^b
NOX2	44.22±9.55	51.41±7.31^a	49.21±3.80^b
NOX4	21.76±5.76	27.37±6.41^a	21.08±5.49^b

P<0.05 vs. CON group

P<0.05 vs. DOX group. CON, control; DOX, doxorubicin; Val, valsartan; NOX, NAD(P)H oxidase; SOD, superoxide dismutase; ROS, reactive oxygen species; BNP, brain natriuretic peptide; ALD, aldosterone; MDA, malondialdehyde.