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. 2020 Sep 2;22(5):3715–3722. doi: 10.3892/mmr.2020.11489

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Copyright: © Xiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — SNHG1 regulates the Wnt/β-catenin signaling pathway to inhibit osteogenic differentiation. Protein expression levels were (A) determined by western blotting and (B) semi-quantified for β-catenin, DKK1, RUNX2, OCN, OPN, OSX and COL1a1 in bone mesenchymal stem cells co-transfected with pcDNA-SNHG1 and miR-101 mimics. *P<0.05 and **P<0.01. SNHG1, small nucleolar RNA host gene 1; DKK1, dickkopf WNT signaling pathway inhibitor 1; RUNX2, RUNX family transcription factor 2; OCN, osteocalin; OPN, osteopontin; OSX, osterix; COL1a1, collagen type I α1 chain; NC, negative control.