Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 18;22(5):4298–4306. doi: 10.3892/mmr.2020.11526

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Overexpression of KNG1 significantly reverses the inhibitory effects of sufentanil on inflammation and oxidative stress. Levels of (A) TNF-α, (B) IL-6, (C) IL-1β and (D) MCP-1 were determined via ELISA. (E) MDA content and the activities of (F) SOD, (G) CAT and (H) GSH-Px were assessed using commercial kits. ***P<0.001 vs. Oe-NC; ^###P<0.001 vs. control; ^ΔP<0.05, ^ΔΔΔP<0.001 vs. LPS + Oe-NC; ^$P<0.05, ^$$P<0.01, ^$$$P<0.001 vs. 40 µM sufentanil + Oe-NC; ^&P<0.05, ^&&P<0.01, ^&&&P<0.001 vs. LPS; ^@P<0.05, ^@@P<0.01, ^@@@P<0.001 vs. LPS + 40 µM sufentanil + Oe-NC. KNG1, kininogen-1; TNF-α, tumor necrosis factor-α; IL, interleukin; MCP-1, monocyte chemoattractant protein-1; MDA, malondialdehyde; SOD, superoxide dismutase; CAT, catalase; GSH-Px, glutathione peroxidase; Oe, overexpression; NC, negative control.