Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 2;22(5):3785–3794. doi: 10.3892/mmr.2020.11486

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Mou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 5. — miRNA-101b targets TGFβRI. (A) Diagram of the binding sites between TGFβRI and miRNA-101b. Red text represents the mutant sequence of TGFβRI (B) Relative luciferase activity of the wild-type and 3′-untranslated region mutant constructs of TGFβRI co-transfected with miR-101b mimics and miRNA control. (C) The mRNA expression levels of TGFβRI in db/db mice. (D) The mRNA expression levels of TGFβRI in the high glucose treated MES13 cells. **P<0.01 Control mimics + wild-type TGFβRI group vs. miR-101b mimics + wild-type TGFβ RI group; ▲P<0.05 db/db group vs. Db/dm group; ^##P<0.01 5.5 mM glucose treated group vs. 30 mM glucose treated group. miR/miRNA, microRNA; TGFβR1, TGFβ receptor 1.