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. 2020 Sep 15;22(5):4221–4226. doi: 10.3892/mmr.2020.11510

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Copyright: © Davies et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Single cell analysis of the hypothalamic Arc-ME complex, using the Single Cell Portal, revealed distinct expression of NRP1. (A) Arc-ME single-cell transcriptomics data are displayed as a spectral tSNE plot of 20,921 cells, coloured per density clustering and annotated according to known cell types. (B) Sub-populations of cell types which are enriched for NRP1 expression, with expression intensity demonstrated by a heat map. (C) Single cell analysis of the hypothalamic Arc-ME complex, using the Single Cell Portal, enriched for population subtypes, represented as violin plots. Arc-ME, arcuate and median eminence; tSNE, T-distributed Stochastic Neighbor Embedding.