Figure 2.

2D anti-migratory effects of the selected extracts at both GI₅₀, MNTC and reference compound (HU 75 µM) on B16-F10 murine melanoma cells for 24 h. Area of the gap (measured in pixels) in a confluent cell monolayer immediately after gap generation (0 h) and at 24 h post-wounding (n = 3) with representative microscopy images for the treated gaps. The significance of inhibitory effect was determined by one-way ANOVA followed by Bonferroni’s post-test with respect to t24 control; Data are presented as the mean ± SD (n = 3), (***) p < 0.001; (**) p < 0.01; (*) p < 0.05, respectively.