TABLE 1.

CRISPR/Cas9 β-arrestin gene editing obtained by sequencing analysis.

Sample	β1 Exon 3	β1 Exon 5	β2 Exon 2	β2 Exon 3
wt	wt/wt	wt/wt	wt/wt	wt/wt
β1 KO	HDR/HDR	HDR/edited	wt/wt	wt/wt
β2 KO	wt/wt	wt/wt	Edited/edited	Edited/edited
β1/2 KO	HDR/HDR	Edited/edited	Edited/edited	Edited/edited

Gene editing of the β-arrestin1 exon 3, and 5, and β-arrestin2 exon 2, and 3, targeted by CRISPR/Cas9 plasmids, performed on genomic DNA from wt, or β-arrestins KO HeLa cells. HDR represents the sequence encoding for the puromycin resistance.