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. 2020 Sep 15;11:569282. doi: 10.3389/fmicb.2020.569282

FIGURE 2.

FIGURE 2

Overview of bacterial As(III) oxidation and chemotaxis. AioX binds As(III) and delivers the signal to the histidine kinase, AioS, simulating autophosphorylation of AioS. Autophosphorylated AioS then phosphorylates its cognate response regulator AioR, and subsequently AioR binds to the promoter of As(III) oxidase, which encodes aioBA genes, to switch on AioBA expression. Furthermore, AioR regulates expression of the As(III) chemoreceptor-encoding gene, mcp. Mcp detects the As(III) concentration gradient and then transports the signal to the flagellum via the chemotaxis system, CheWAY. Ultimately, the GW4 strain exhibits chemotaxis toward As(III).