Table 6. Costs, RIG administrations and ICER as a result of a 1.5-fold increased rabies vaccination uptake for diverse risk groups, the Netherlands, 2018 .

Risk group	Travellers < 35 years	Travellers to south-eastern and western Asia	Men	Travellers to South America	Travellers having at least one risk factor	Travellers having all risk factors togethera
Additional vaccinated persons	11,970	9,800	8,570	1,800	17,290	3,410
95% UI	2,850–22,100	1,880–18,530	1,280–16,540	−3,280–6,730b	51,60–31,160	−1,750–8,810b
Avoided number of RIG administrations	45	41	29	4	60	16
Additional costs	1,206,000	966,400	867,100	188,900	1,755,100	333,100
95% UI	226,000–2,413,900	421,000–2,290,000	77.400–1,819,800	−391,900–765,300b	482,700–3,341,000	−260,600–941,800b
ICER: Incremental costs per additional vaccinated person	101	99	101	105	102	98
95% UI	82–116	71–116	0.75–118.0	71–151	88–116	26–181
ICER: Incremental costs per avoided RIG administration	26,970	23,760	30,370	46,750	29,220	21,320
95% UI	9,530–52,460	5,790–49,510	5,323–64,110	−129,950–229,830b	14,250–53,000	−24,010–70,190b

ICER: incremental cost-effectiveness ratio; RIG: rabies immunoglobulin; UI: uncertainty interval.

^a This group consist of men younger than 35 years travelling to south-eastern and western Asia.

^b Owing to low numbers in this specific risk group, the UI are not interpretable.

The table presents averages with 95% UI. Note that in Table 4 total costs per vaccinated persons are presented, whereas in Table 5 the incremental costs per additional vaccinated person are presented, and they are therefore not comparable. For full details see Supplementary Table S3.