Fig. 2.

Deletion of Fermt3 prolongs lifespan. (A) Kaplan–Meier survival curve of BA⁺K3^WT and BA⁺K3^KO mixed chimeras treated orally (p.o.) with tamoxifen before tetracycline withdrawal (n = 18). (B) BA^condK3^cond mixed chimeras first withdrawn from tetracycline (BA⁺) followed by tamoxifen (K3^KO) or oil (K3^WT) treatment. (C) Kaplan–Meier survival curve of BA⁺K3^WT and BA⁺K3^KO mixed chimeras treated with tamoxifen after tetracycline withdrawal (n ≥ 12). Statistics by log-rank test. ***P < 0.001.