Table 2.

Amplitudes of RB SCNAs Are Significantly Higher In the Setting of Clinical Progression (Relative to Baseline) Than Regression (P < 0.05)

	SCNA Amplitude (Mean ± SD)
SCNA	Clinical Progression	Clinical Regression	P Valuea
6p gain (11 eyes)	0.666 ± 0.353	0.228 ± 0.379	0.0008
1q gain (10 eyes)	0.472 ± 0.261	0.244 ± 0.233	0.043
16q loss (8 eyes)	0.351 ± 0.132	0.186 ± 0.175	0.032
2p gain (5 eyes)	0.283 ± 0.124	0.119 ± 0.139	0.019

SCNA amplitude is represented by the absolute amplitude—determined by |1 − ratio to the median|—for both copy number gains and copy number losses. SD, standard deviation.

^aMann-Whitney U test.