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. 2020 Mar 20;67(2):188–198. doi: 10.3164/jcbn.19-87

Table 2.

Body weight, energy intake, energy expenditure and inflammation index

AD-CON (n = 10) AD-KD (n = 10) AD-IMF (n = 10) AD-CHO (n = 10) Non-AD-CON (n = 10)
Final body weight (g) 366 ± 27ab 353 ± 32b 291 ± 27d 317 ± 26c 373 ± 15a
Body weight gain (g) 169 ± 12a 165 ± 15a 94.4 ± 8.4c 117 ± 14b 175 ± 9.2a
Epididymal fat pads/body weight (g/kg body weight) 11.3 ± 1.0a 11.0 ± 0.7a 9.9 ± 0.5b 10.1 ± 0.8b 11.0 ± 1.0a
Retroperitoneal fat/body weight (g/kg body weight) 11.1 ± 0.7a 11.3 ± 0.9a 9.8 ± 0.9b 9.2 ± 0.7b 11.1 ± 1.0a
Visceral fat (g/kg body weight) 22.4 ± 1.6a 22.3 ± 1.4a 19.7 ± 1.1b 19.3 ± 1.7b 22.1 ± 1.9a
Food intake (g/day) 16.6 ± 1.8a 9.7 ± 1.0b 10.3 ± 2.1b 15.8 ± 1.7a 16.7 ± 1.6a
Energy intake (kcal/day) 71.3 ± 7.7a 63.8 ± 6.6b 44.4 ± 9.0c 61.5 ± 6.6b 71.6 ± 6.9a
Energy expenditure (kcal/body weight/day) 103 ± 10ab 110 ± 11a 117 ± 12a 110 ± 11a 94 ± 11b
Respiratory quotient 0.86 ± 0.09ab 0.81 ± 0.09b 0.82 ± 0.09b 0.92 ± 0.08a 0.81 ± 0.08b
Carbohydrate oxidation during dark cycle (mg/kg body weight/min) 5.8 ± 0.7b 4.1 ± 0.7c 4.7 ± 0.7c 8.7 ± 0.9a 3.5 ± 0.5d
Fat oxidation during dark cycle (mg/kg body weight/min) 5.2 ± 0.6c 7.6 ± 0.8a 7.8 ± 0.9a 3.0 ± 0.4d 6.5 ± 0.8b

The amyloid-β(25–35) infused diabetic rats AD model rats received assigned diet for 8 weeks as follows: 1) a normal diet (28 energy % fat diet) with ad libitum feeding (AD-CON), 2) ketogenic diet (AD-KD; 0.1% carbohydrate diet), 3) high carbohydrate diet (AD-CHO; 68 energy % carbohydrate diet) and 4) normal diet with intermittent fasting (AD-IMF). The sham-operated rats received the same diet (normal diet) as AD-CON (Non-AD-CON) for 8 weeks. Values represent means ± SD. a,b,c,dDifferent superscripts after SD indicate significant differences at p<0.05.