Table 2.
Responses to treatment.
| Variable | FOLFIRINOX (n = 15) |
FOLFOX-6 (n = 32) |
FOLFIRI (n = 30) |
p value |
|---|---|---|---|---|
| Response – n. (%) | ||||
| • Complete response | 0 (0%) | 0 (0%) | 0 (0%) | |
| • Partial response | 7 (46%) | 6 (18%) | 4 (13%) | |
| • Stable disease | 4 (26%) | 13 (40%) | 4 (13%) | |
| • Progressive disease | 3 (20%) | 13 (40%) | 22 (73%) | |
| • Could not be evaluated | 1 (6%) | 0 (0%) | 0 (0%) | |
| Rate of objective response | 0.033 | |||
| • n. (%) | 7 (46%) | 6 (18%) | 4 (13%) | |
| Rate of disease control | 0.004 | |||
| • n. (%) | 11 (78%) | 19 (59%) | 8 (26%) |
None of the patients’ characteristics independently influenced the outcomes in terms of PFS (Supplemental Figure S1), OS1 (Supplemental Figure S2), or OS2 (Supplemental Figure S3).
OS1, overall survival curves from the start of first-line treatment; OS2, overall survival curves from the start of second-line treatment; PFS, progression-free survival.