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. 2020 Sep 17;89(7):1810–1817. doi: 10.1038/s41390-020-01159-x

Table 4.

Respiratory variability and extubation outcomes.

MV ETT-CPAP
Success Failure P values Success Failure P values
BB intervals (s)
  SDBB 0.55 [0.27–0.56] 1.02 [0.90–1.42] 0.014 0.36 [0.27–0.39] 0.61 [0.42–1.31] 0.014
  CVBB 0.48 [0.36–0.67] 0.50 [0.38–0.77] 0.945 0.37 [0.33–0.39] 0.40 [0.31–0.61] 0.945
  SDSDBB 0.60 [0.34–0.73] 1.07 [1.00–1.70] 0.014 0.40 [0.37–0.45] 0.70 [0.52–1.32] 0.002
  TIBB 2.92 [2.46–3.36] 3.65 [2.67–4.15] 0.628 3.06 [2.69–3.76] 3.04 [2.64–3.45] 0.945
Breath area (μV·s)
  SDArea 248 [169–346] 347 [315–419] 0.294 269 [220–392] 384 [304–473] 0.366
  CVArea 0.67 [0.62–0.78] 0.91 [0.86–0.98] 0.014 0.58 [0.53–0.65] 0.83 [0.64–0.99] 0.013
  SDSDArea 2789 [179–426] 436 [404–467] 0.294 334 [272–486] 480 [379–631] 0.366
  TIArea 4.33 [3.08–5.67] 3.86 [3.45–4.69] 0.534 5.43 [3.76–7.45] 4.60 [3.44–6.79] 0.534
Neural Ti (s)
  SDNTi 0.29 [0.18–0.33] 0.64 [0.55–0.81] 0.014 0.20 [0.18–0.21] 0.40 [0.27–0.57] 0.035
  CVNTi 0.60 [0.44–0.69] 1.05 [0.84–1.33] 0.008 0.42 [0.42–0.48] 0.59 [0.53–0.93] 0.001
  SDSDNTi 0.41 [0.24–0.45] 0.81 [0.68–1.16] 0.022 0.25 [0.23–0.26] 0.49 [0.37–0.74] 0.014
  TINTi 2.85 [2.36–3.39] 3.52 [2.60–4.15] 0.534 2.65 [2.49–3.35] 3.46 [2.80–4.37] 0.347
Neural Te (s)
  SDNTe 0.35 [0.21–0.43] 0.62 [0.48–0.70] 0.014 0.27 [0.20–0.30] 0.37 [0.26–1.04] 0.234
  CVNTe 0.53 [0.37–0.57] 0.75 [0.73–0.79] 0.021 0.42 [0.35–0.46] 0.63 [0.49–0.96] 0.021
  SDSDNTe 0.37 [0.27–0.56] 0.76 [0.54–0.89] 0.073 0.32 [0.28–0.35] 0.43 [0.33–1.44] 0.138
  TINTe 4.04 [3.09–4.81] 5.01 [4.81–5.83] 0.138 3.57 [3.38–4.49] 3.76 [3.44–6.77] 0.836
Breath amplitude (μV)
  SDAmp 6.29 [3.76–7.13] 6.40 [5.31–8.67] 0.534 4.97 [4.64–9.05] 7.66 [6.56–8.92] 0.445
  CVAmp 0.58 [0.55–0.62] 0.74 [0.71–0.79] 0.001 0.49 [0.46–0.53] 0.70 [0.60–0.75] 0.002
  SDSDAmp 7.57 [4.17–8.69] 8.26 [6.87–9.68] 0.062 6.45 [6.16–11.31] 9.87 [8.76–10.61] 0.445
  TIAmp 2.55 [1.90–3.14] 2.53 [2.12–3.15] 0.836 2.48 [2.14–3.63] 2.42 [1.70–3.29] 0.534
Breath width (s)
  SDWidth 0.13 [0.12–0.17] 0.19 [0.14–0.31] 0.234 0.11 [0.10–0.13] 0.16 [0.12–0.20] 0.138
  CVWidth 0.36 [0.32–0.43] 0.46 [0.37–0.70] 0.279 0.33 [0.28–0.34] 0.38 [0.32–0.49] 0.276
  SDSDWidth 0.17 [0.15–0.24] 0.26 [0.19–0.45] 0.181 0.16 [0.14–0.18] 0.23 [0.16–0.27] 0.138
  TIWidth 2.56 [2.45–2.74] 2.75 [2.53–2.89] 0.628 2.30 [2.20–2.78] 2.73 [2.37–3.34] 0.389

MV mechanical ventilation, ETT-CPAP endotracheal tube continuous positive airway pressure, BB breath to breath, SD standard deviation, CV coefficient of variation, SDSD standard deviation of successive differences, TI triangular index, NTi neural inspiratory time, Ti inspiratory time, Te expiratory time.

Values are presented as median [IQR].