TABLE 1.
Demographic and clinical characteristics of controls and patients
| Demographic and Clinical Characteristics | Age‐Matched Controls, n = 128 | Patients with Recently Diagnosed Parkinsonism, n = 79 | Patients with PD with a Previous Diagnosis, n = 71 | P Value |
|---|---|---|---|---|
| Age, y, mean ± SD (range) | 76.7 ± 8.0 (63–92) | 78.3 ± 7.3 (60–93) | 79.4 ± 8.5 (60–95) | 0.074** |
| Sex, female, n (%) | 79 (61.2) | 48 (60.8) | 36 (50.7) | 0.292* |
| MMSE score, mean ± SD (range) | 27.3 ± 2.7 (22–30) | 26.4 ± 3.2 (22–30) | 0.072** | |
| Years of schooling, mean ± SD (range) | 9.8 ± 2.4 (6–16) | 9.7 ± 2.6 (6–16) | 0.841** | |
| Disease duration, mo, mean ± SD (range) | 7.1 ± 10.5 (0–48) | 47.4 ± 47.1 (3–276) | <0.0001** | |
| UPDRS Part III score, mean ± SD (range) | 6.3 ± 1.9 (5–14) | 10.9 ± 3.2 (5–20) | <0.0001** | |
| VSRAD z score, mean ± SD (n) | 1.07 ± 0.54 (75) | 1.24 ± 0.64 (68) | 0.087** |
*
P values were assessed by Fisher exact test.
**
P values were assessed by analysis of variance.
PD, Parkinson's disease; SD, standard deviation; MMSE, Mini‐Mental State Examination; UPDRS, Unified Parkinson's Disease Rating Scale; VSRAD, voxel‐based specific regional analysis system for Alzheimer's disease.