Table 3. Sensitivity and specificity for fracture risk at the DF and PT using different FN or TH T-score values in participants with SCI.

			DF/PT aBMD (≤ 0.60g/cm2)
FN/TH T-score cutoffs			HFR	LFR	Sensitivity	Specificity
	<−3.5 SD	HFR	5	3	33%	97%
		LFR	10	89
			HFR	LFR	Sensitivity	Specificity
	<−2.5 SD	HFR	17	20	100%	77%
		LFR	0	68
			HFR	LFR	Sensitivity	Specificity
	<−3.1 SD	HFR	13	6	76%	93%
		LFR	4	82

FN and TH cutoff values: <−3.5 SD (a value that has been used as an exclusion criterion for entry into EAW protocols), <−2.5 SD (WHO criteria to diagnose osteoporosis), and <−3.1 SD (a value obtained from the ROC curve T-score_YI and linear regression T-score predicted at the TH from the DF); DF/PT cutoff value used was <0.60 g/cm2.

HFR, high fracture risk; LFR, lower fracture risk; DF, distal femur; PT, proximal tibia; TH, total hip; FN, femoral neck; SD, standard deviation; ROC, receiver operating characteristic; T-score_YI, Youden Index T-score cutoff of −3.1 SD.

 Sensitivity = True-Positive/(True-Positive + False-Negative)

 Specificity = True-Negative/(False-Positive + True-Negative)