Table 1. Summary results for IgM and IgG detection in 798 plasma samples from patients with/without COVID-19.
| Variables | COVID-19 patients, n (%) | Non-COVID-19 patients, n (%) | Sensitivity (%, 95%CI) |
Specificity (%, 95%CI) |
Kappa | |
|---|---|---|---|---|---|---|
| Total | 409 | 389 | ||||
| Age | median (IQR) | 60 (49–69) | 45 (29–61) | |||
| Sex | ||||||
| Male | 217 (53.06) | 224 (57.58) | ||||
| Female | 192 (46.94) | 165 (42.42) | ||||
| IgM | 87.04 (83.77–90.31) | 96.92 (95.19–98.64) | 0.84 | |||
| Positive | 356 (87.04) | 12 (1.05) | ||||
| Negative | 53 (12.96) | 377 (98.95) | ||||
| IgG | 87.04 (83.77–90.31) | 96.92 (95.19–98.64) | 0.84 | |||
| Positive | 356 (87.04) | 12 (1.05) | ||||
| Negative | 53 (12.96) | 377 (98.95) | ||||
| IgM/IgG | 88.75 (85.68–91.83) | 96.14 (94.22–98.07) | 0.85 | |||
| Positive | 363 (88.75) | 15 (1.84) | ||||
| Negative | 46 (11.25) | 374 (98.16) |
Abbreviation: IQR, interquartile range; CI, confidence interval.
IgM/IgG: at least one positive result detected by IgM and IgG.
The time between the symptoms onset and the collection of serum samples ranged from 1 to 87 days.