Table 5.
The effect of β-sitosterol on the arthritic score of CFA-induced arthritic rats.
| S. No | Groups | Arthritic
Score |
|||
|---|---|---|---|---|---|
| Day 7 | Day 14 | Day 21 | Day 28 | ||
| 1 | CFA | 4.1 ± 0.73 | 5.4 ± 0.89 | 6.9 ± 0.78 | 7.8 ± 0.78 |
| 2 | CFA+ β-sitosterol (2.5 mg/kg) | 3.9 ± 0.78* | 4.9 ± 0.78** | 5.6 ± 0.83*** | 4.8 ± 0.78*** |
| 3 | CFA+ β-sitosterol (25 mg/kg) | 3.5 ± 0.78** | 3.4 ± 0.63*** | 2.9 ± 0.67*** | 2.5 ± 0.73*** |
| 4 | CFA+ β-sitosterol-SLN | 3 ± 0.67*** | 2.1 ± 0.54*** | 1.3 ± 0.28*** | 0.6 ± 0.02*** |
| 5 | CFA + Indomethacin (400µg/kg) | 3.2 ± 0.34*** | 2.3 ± 0.59*** | 1.7 ± 0.31*** | 1 ± 0.09*** |
All values are presented as mean ± SEM. Statisticalanalysis by one-way ANOVA followed by Dunnett’s multiple comparison. *p < .05, **p < .01 and ***p < .01 vs. Control.