Table 6.
The effect of β-sitosterol on the antioxidant parameter of CFA-induced arthritic rats.
| S. No | Groups | Antioxidant
parameters |
|||
|---|---|---|---|---|---|
| TBARS (nmol/g) | SOD (U/mgprotein) | CAT (U/mgprotein) | GSH (µg/g) | ||
| 1 | NC | 56.66 ± 2.93 | 5.43 ± 1.02 | 5.34 ± 1.14 | 0.39 ± 0.04 |
| 2 | CFA | 92.34 ± 4.32 | 1.67 ± 0.89 | 1.76 ± 0.83 | 0.11 ± 0.02 |
| 3 | CFA+ β-sitosterol (2.5 mg/kg) | 83.45 ± 2.04* | 1.98 ± 0.93* | 2.1 ± 0.98* | 0.15 ± 0.03* |
| 4 | CFA+ β-sitosterol (25 mg/kg) | 72.34 ± 2.93** | 2.85 ± 0.99** | 3.03 ± 0.94** | 0.21 ± 0.04** |
| 5 | CFA+ β-sitosterol-SLN | 59.65 ± 3.43*** | 4.75 ± 1.03*** | 5.02 ± 0.87*** | 0.34 ± 0.07*** |
| 6 | CFA + Indomethacin (400µg/kg) | 61.03 ± 2.83*** | 4.32 ± 1.02*** | 4.98 ± 0.98*** | 0.32 ± 0.06*** |
All values are presented as mean ± SEM. Statisticalanalysis by one-way ANOVA followed by Dunnett’s multiple comparison. *p < .05, **p < .01 and ***p < .01 vs. Control.