Table 7.
The effect of β-sitosterol on the hematological parameters of CFA-induced arthritic rats.
| S. No | Groups | Hematological parameters |
|||
|---|---|---|---|---|---|
| WBC | RBC | Hb | ESR | ||
| 1 | NC | 6.45 ± 1.02 | 8.02 ± 1.04 | 13.2 ± 1.31 | 9.04 ± 1.02 |
| 2 | CFA | 8.78 ± 1.12 | 3.48 ± 1.11 | 6.75 ± 1.28 | 14.53 ± 1.04 |
| 3 | CFA+ β-sitosterol (2.5 mg/kg) | 8.34 ± 1.01* | 4.02 ± 1.02** | 7.14 ± 0.83* | 13.89 ± 0.98** |
| 4 | CFA+ β-sitosterol (25 mg/kg) | 7.78 ± 0.98** | 6.03 ± 0.85*** | 8.98 ± 0.91*** | 12.45 ± 0.78*** |
| 5 | CFA+ β-sitosterol-SLN | 6.76 ± 0.79*** | 7.84 ± 1.01*** | 12.8 ± 1.83*** | 9.34 ± 0.77*** |
| 6 | CFA + Indomethacin (400µg/kg) | 6.97 ± 0.83*** | 7.67 ± 0.89*** | 12.67 ± 1.92*** | 9.45 ± 0.69*** |
All values are presented as mean ± SEM. Statisticalanalysis by one-way ANOVA followed by Dunnett’s multiple comparison. *p < .05, **p < .01 and ***p < .01 vs. Control.