Table 8.
The effect of β-sitosterol on the hepatic parameters of CFA-induced arthritic rats.
| S. No | Groups | Hepatic
parameters |
||
|---|---|---|---|---|
| AST (U/L) | ALT (U/L) | ALP (U/L) | ||
| 1 | NC | 40.3 ± 2.34 | 45.3 ± 1.03 | 78.5 ± 2.34 |
| 2 | CFA | 142.3 ± 3.45 | 170.3 ± 2.12 | 411.3 ± 6.56 |
| 3 | CFA+ β-sitosterol (2.5 mg/kg) | 132.3 ± 4.23* | 155.6 ± 3.12** | 350.3 ± 4.95** |
| 4 | CFA+ β-sitosterol (25 mg/kg) | 100 ± 2.34** | 111.3 ± 3.84*** | 280.4 ± 3.89*** |
| 5 | CFA+ β-sitosterol-SLN | 50.4 ± 1.89*** | 60.3 ± 2.92*** | 100.3 ± 3.84*** |
| 6 | CFA + Indomethacin (400µg/kg) | 55.8 ± 2.93*** | 69.4 ± 3.01*** | 111.5 ± 4.56*** |
All values are presented as mean ± SEM. Statisticalanalysis by one-way ANOVA followed by Dunnett’s multiple comparison. *p < .05, **p < .01 and ***p < .01 vs. Control.