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. 2020 Sep 6;9(1):1943–1954. doi: 10.1080/22221751.2020.1812435

Figure 5.

Figure 5.

Transcriptome analysis of ME49 post-infection. (A) Differentially expressed genes of ME49 post-infection. Noninfectious ME49 was used as a control (|fc| ≥ 2, raw p-value < 0.05). A heat map was generated using Cluster grammer (http://amp.pharm.mssm.edu/clustergrammer/). (B) Volume plot showing differential expression of ME49 genes between 0 and 72 h post-infection (|fc| ≥ 2, raw p-value < 0.05). The top 5 gene names are indicated. (C) KEGG pathway analysis was performed using the differentially expressed genes (DEGs) of ME49 (|fc| ≥ 2, raw p-value < 0.05). (D) Gene Ontology (GO) annotation of T. gondii postinfection of cerebral organoids; p-value < 0.01. MF, molecular function; BP, biological process; and CC, cellular component.