Table 3.
Association between carbapenem resistance, appropriate antibiotic treatment within 24 h, and 30-days attributable mortality, stratified by capsular types.
| Non-2/10/22/52 (n = 137) | 2/10/22/52 (n = 100) | P of interaction | |||
|---|---|---|---|---|---|
| OR (95% CI)* | p-value | OR (95% CI)* | p-value | ||
| Sex | 1.47 (0.54–4.01) | 0.45 | 0.75 (0.25–2.32) | 0.62 | 0.43 |
| Age | 1.03 (0.99–1.07) | 0.18 | 0.99 (0.95–1.04) | 0.79 | 0.58 |
| Charlson score | 1.10 (0.89–1.35) | 0.39 | 1.13 (0.90–1.42) | 0.30 | 0.92 |
| Pneumonia | 1.64 (0.58–4.61) | 0.35 | 3.89 (1.20–12.63) | 0.02 | 0.37 |
| Pitt score | 1.43 (1.21–1.69) | <0.0001 | 1.40 (1.15–1.70) | 0.0007 | 0.70 |
| Appropriate empirical antimicrobial therapy a within 24 h | 1.50 (0.51–4.39) | 0.46 | 0.19 (0.06–0.66) | 0.008 | 0.02 |
| Carbapenem resistance | 3.86 (0.88–16.93) | 0.07 | 7.90 (1.25–49.82) | 0.03 | 0.33 |
a
appropriate empirical antimicrobial therapy within 24 h was defined by in vitro susceptibility test.
*estimated from logistic regression model.