Table 4.
Species clusters in C/MIP disease and healthy sites before and after treatment.
| Time point | DD (>50% prevalent species)* | DD∩DH (>50% prevalent species)† | DH (>50% prevalent species)‡ |
|---|---|---|---|
| BL | Aggregatibacter actinomycetemcomitans HOT-531_m | Campylobacter concisus and rectus HOT-575/748_m | Capnocytophaga sp HOT-335_m |
| Fusobacterium periodontium HOT-201 | Campylobacter gracilis HOT-623_m | Eubacterium[11][G 3] brachy HOT-557_m | |
| Prevotella Cluster IV HOT-658 693/714/782 | Campylobacter showae HOT-763_m | Eubacterium[11][G 7] yurii HOT-377_m | |
| Tannerella forsythia HOT-613 | Catonella morbi and sp clone HOT-164/165 | Selenomonas infelix and sp clones HOT-126/479/481/639_m | |
| Fusobacterium nucleatum ss nucleatum and animalis HOT-420_m | Streptococcus anginosus and gordonii HOT-543/622_m | ||
| Gemella haemolysans HOT-626_m | |||
| Gemella morbillorum HOT-046_m | |||
| Haemophilus parainfluenzae HOT-718 | |||
| Neisseria Cluster II HOT-014/609/682/764 | |||
| Parvimonas micra HOT-111_m | |||
| Streptococcus constellatus and intermedius HOT-576/644_m | |||
| Streptococcus oralis and sp clones HOT-064/707 | |||
| 3M | Eubacterium[11][G 7] yurii HOT-377_m | Campylobacter concisus and rectus HOT-575/748_m | Capnocytophaga granulosa HOT-325_m |
| Prevotella Cluster IV HOT-658 693/714/782 | Campylobacter gracilis HOT-623_m | Eikenella corrodens and Kingella denitrificans and sp clone HOT-012/577/582_m | |
| Campylobacter showae HOT-763_m | Fusobacterium periodontium HOT-201 | ||
| Catonella morbi and sp clone HOT-164/165 | Kingella oralis HOT-706_m | ||
| Fusobacterium Cluster | Neisseria elongata HOT-598 | ||
| Gemella haemolysans HOT-626_m | Prevotella oris HOT-311_m | ||
| Gemella morbillorum HOT-046_m | Selenomonas infelix and sp clones HOT-126/479/481/639_m | ||
| Granulicatella adiacens HOT-534_m | Streptococcus australis HOT-073_m | ||
| Granulicatella elegans HOT-596_m | Streptococcus cristatus and sp clone HOT-058/578 | ||
| Haemophilus parainfluenzae HOT-718 | Streptococcus salivarius HOT-755_m | ||
| Neisseria Cluster II HOT-014/609/682/764 | Streptococcus sp strains HOT-070/071 | ||
| Parvimonas micra HOT-111_m | Veillonella dispar HOT-160/Veillonella parvula HOT-161 | ||
| Streptococcus anginosus and gordonii HOT-543/622_m | Veillonella sp clones HOT-780 | ||
| Streptococcus constellatus and intermedius HOT-576/644_m | |||
| Streptococcus mitis bv2 HOT-398_m | |||
| Streptococcus oralis and sp clones HOT-064/707 | |||
| 6M | Campylobacter Cluster II HOT-580/748/763 | Campylobacter concisus and rectus HOT-575/748_m | Capnocytophaga granulosa HOT-325_m |
| Neisseria Cluster II HOT-014/609/682/764 | Campylobacter gracilis HOT-623_m | Cardiobacterium hominis HOT-633_m | |
| Streptococcus Cluster III HOT-755/758/767/768 | Campylobacter showae HOT-763_m | Eikenella corrodens and Kingella denitrificans and sp clone HOT-012/577/582_m | |
| Tannerella forsythia HOT-613 | Catonella morbi and sp clone HOT-164/165 | Fusobacterium Cluster | |
| Eubacterium[11][G 3] brachy HOT-557_m | Fusobacterium periodontium HOT-201 | ||
| Fusobacterium nucleatum ss nucleatum and animalis HOT-420_m | Prevotella oris HOT-311_m | ||
| Gemella haemolysans HOT-626_m | Propionibacterium propionicum HOT-739_m | ||
| Gemella morbillorum HOT-046_m | Rothia dentocariosa and mucilaginosa HOT-587/681 | ||
| Granulicatella adiacens HOT-534_m | Selenomonas infelix and sp clones HOT-126/479/481/639_m | ||
| Granulicatella elegans HOT-596_m | Selenomonas noxia and sp clone HOT-130/140 | ||
| Haemophilus parainfluenzae HOT-718 | Solobacterium moorei HOT-678_m | ||
| Parvimonas micra HOT-111_m | Streptococcus australis HOT-073_m | ||
| Prevotella Cluster IV HOT-658 693/714/782 | Streptococcus mitis bv2 HOT-398_m | ||
| Streptococcus anginosus and gordonii HOT-543/622_m | Streptococcus salivarius HOT-755_m | ||
| Streptococcus constellatus and intermedius HOT-576/644_m | Veillonella atypica HOT-524_m | ||
| Streptococcus oralis and sp clones HOT-064/707 | Veillonella dispar HOT-160/Veillonella parvula HOT-161 |
*Species present in ≥ 50% of DD sites and < 50% of DH sites; † Species present in ≥ 50% of both DD and DH sites; ‡ Species present in ≥ 50% DH sites and < 50% DD sites. DD – C/MIP disease sites, DH- C/MIP healthy sites. Bold species are in the same group at all time points.