Table 3.
Outcome measures in patients of rheumatoid arthritis treated with diclofenac, meloxicam, and celecoxib
| Diclofenac (n=10) |
Meloxicam (n=10) |
Celecoxib (n=10) |
||||
|---|---|---|---|---|---|---|
| Baseline | Final | Baseline | Final | Baseline | Final | |
| Tender joints count (n) | 33.8±1.93 | 23.4±1.87* | 33.3±2.06 | 22.4±1.26* | 31.5±1.77 | 20.8±1.27* |
| Change (%)# | 30 | 32 | 33.80 | |||
| Swollen joints count (n) | 23.2±1.19 | 14.7±0.59* | 21.8±1.70 | 15.4±1.10* | 20.8±1.67 | 13.2±0.79* |
| Change (%)# | 36 | 28.20 | 34.10 | |||
| Patient assessment of pain (VAS)ª | 61.5±3.73 | 38.9±2.08*,$ | 64.5±3.08 | 42.1±2.51* | 66.4±3.41 | 47.2±2.68* |
| Change (%)# | 35 | 34.50 | 27.70 | |||
| Physician global assessment (VAS)ª | 51.4±3.26 | 32.4±1.68*,$ | 51.3±1.28 | 34.7±2.20* | 57.8±2.41 | 41.2±2.44* |
| Change (%)# | 34.60 | 32.20 | 27.80 | |||
| Patient global assessment (VAS)ª | 53.8±3.46 | 36.8±2.05*,$ | 58.0±3.27 | 38.5±2.62* | 60.4±3.12 | 43.8±2.11* |
| Change (%)# | 30.70 | 32.40 | 26.20 | |||
| Patient assessment of physical function on modified MHAQ§ | 17.4±1.93 | 12.7±0.63* | 17.3±1.14 | 12.1±0.48* | 16.3±0.83 | 11.9±0.46* |
| Change (%)# | 25.30 | 28.20 | 25.80 | |||
ªScore of 0 is best, 10 is worst; §Score of 8 is best, 32 is worst; #Based on mean values; *P<0.001 baseline versus final values in corresponding treatment groups; $P<0.05 versus celecoxib group at end of week 12. All values expressed as mean±SE. VAS: Visual analog scale (mm); MHAQ: Modified health assessment questionnaire; SE: Standard error