Figure 3.

A-C, Alternative neoplastic entities presenting as persistent subsolid nodules. A, Mucosa-associated lymphoid tissue: 81-year-old woman with subsolid right upper lobe nodule proven to be extranodal marginal zone lymphoma with plasmacytic differentiation on resection. Lymphomas may be uni- or multifocal and, unlike multiple synchronous primary lung adenocarcinomas, usually progress in unison. B, GI adenocarcinoma metastases: 54-year-old man with colorectal adenocarcinoma, and a left upper lobe metastasis with internal bubble lucencies. C, Melanoma: 79-year-old man with melanoma confined to the ear 4 years prior, with new mixed solid and subsolid nodule, with posterior solid component doubling in size over 3 months (baseline image not shown). On resection, the nodule was found to be metastatic melanoma.