. 2020 Oct 5;15(10):e0240228. doi: 10.1371/journal.pone.0240228

Table 1. Mean, confidence interval, total, intra- and inter-subject variabilities of outcome parameters between [¹⁸F]FDG test and retest scans.

A)	CMRglu (μmol/min/100g)					B)	SUV (g/mL)
	Mean ± sd	95% CI	Abs var	IntraSV	InterSV	Mean ± sd	95% CI	Abs var	IntraSV	InterSV
	(n = 12)	(relative value)	(%; )	(%; n = 6)	(%; n = 6)	(n = 12)	(relative value)	(%;)	(%; n = 6)	(%; n = 6)
	(n = 12)	(relative value)	(%; )	[EV,%]	[EV,%]	(n = 12)	(relative value)	(%;)	[EV, %]	[EV, %]
Thalamus	20.6±10.1	[0.0;42.8]	42.8±28.5	45.8 [86]	18.6 [14]	2.5±0.5	[1.4; 3.5]	18.9±16.4	18.5 [93]	5.2 [7]
Globus pallidum	19.5±9.3	[0.0;40.0]	34.2±27.3	39.5 [67]	27.7 [33]	2.2±0.4	[1.3; 3.1]	20.2±15.3	18.7 [90]	6.3 [10]
Caudate nucleus	24.9±10.8	[1.2;48.6]	41.8±25.7	41.1 [89]	14.3 [11]	2.7±0.5	[1.5; 3.8]	16.4±16.4	17.4 [76]	9.7 [24]
Putamen	26.2±10.9	[2.2;50.3]	42.3±22.0	38.1 [82]	17.8 [18]	2.8±0.5	[1.7; 3.8]	16.1±15.7	16.5 [90]	5.4 [10]
Cortex	19.4±8.2	[1.5;37.5]	39.9±24.1	38.0 [80]	18.9 [20]	2.2±0.3	[1.5; 2.9]	16.3±12.5	14.8 [94]	3.8 [6]
Midbrain	20.4±9.5	[0.0;41.3]	37.1±29.2	43.5 [86]	17.6 [14]	2.3±0.4	[1.4; 3.3]	18.5±16.7	17.9 [100]	0.0
Pons	15.8±6.9	[0.7;30.9]	25.4±29.2	38.1 [75]	22.0 [25]	1.9±0.3	[1.3; 2.6]	19.0±15.4	16.6 [100]	0.0
Cerebellum	21.1±9.2	[0.8;41.5]	33.2±25.6	36.0 [65]	26.1 [35]	2.3±0.4	[1.6; 3.1]	19.4±10.9	15.8 [100]	0.0
Frontal cortex	26.3±11.1	[2.0;50.6]	40.4±26.8	40.1 [90]	13.1 [10]	2.8±0.5	[1.5; 4.0]	16.3±16.6	17.6 [76]	9.9 [24]
Occipital cortex	17.0±9.0	[0.0;36.8]	38.3±29.6	46.2 [75]	26.6 [25]	2.1±0.4	[1.2; 3.0]	20.5±18.9	21.4 [100]	0.0
C)	SUVR_pons (unitless)					D)	SUVR_Cerebellum (unitless)
	Mean±sd	95% CI	Abs var	IntraSV	InterSV	Mean±sd	95% CI	Abs var	IntraSV	InterSV
	(n = 12)	(relative value)	(%; )	(%; n = 6)	(%; n = 6)	(n = 12)	(relative value)	(%;)	(%; n = 6)	(%; n = 6)
	(n = 12)	(relative value)	(%; )	[EV,%]	[EV, %]	(n = 12)	(relative value)	(%;)	[EV, %]	[EV, %]
Thalamus	1.3±0.1	[1.1 ;1.5]	11.4±8.4	10.2 [100]	0.0	1.0±0.1	[0.8 ;1.2]	8.7±4.5	6.8 [96]	1.3 [4]
Globus pallidum	1.1±0.1	[0.9 ;1.3]	9.5±9.9	9.9 [99]	0.9 [0.8]	0.9±0.1	[0.7 ;1.1]	6.8±4.9	5.9 [80]	3.0 [20]
Caudate nucleus	1.4±0.2	[1.0 ;1.8]	13.0±12.8	13.3 [100]	0.0	1.1±0.1	[0.9 ;1.4]	9.8±7.5	8.5 [84]	3.7 [16]
Putamen	1.4±0.1	[1.2 ;1.7]	11.8±11.6	11.8 [100]	0.0	1.2±0.1	[1.0 ;1.4]	8.6±6.8	7.5 [98]	0.9 [2]
Cortex	1.1±0.1	[0.9 ;1.4]	10.3±11.3	10.9 [100]	0.0	0.9±0.1	[0.7 ;1.1]	7.1±5.9	6.3 [100]	0.0
Midbrain	1.2±0.1	[1.0 ;1.4]	9.1±6.7	7.9 [100]	0.0	1.0±0.1	[0.8 ;1.2]	6.4±5.0	5.7 [92]	1.6 [8]
Pons						0.8±0.1	[0.6 ;1.0]	6.8±6.7	6.4 [96]	1.2 [4]
Cerebellum	1.2±0.1	[1.0 ;1.4]	6.8±6.7	6.5 [99]	0.3 [0.1]
Frontal cortex	1.4±0.2	[1.0 ;1.8]	13.9±14.6	15.2 [100]	0.0	1.2±0.1	[1.0 ;1.4]	10.7±8.2	9.5 [78]	5.1 [22]
Occipital cortex	1.1±0.1	[0.9 ;1.3]	10.5±8.8	9.7 [100]	0.0	0.9±0.1	[0.7 ;1.1]	9.8±7.2	8.5 [100]	0.0
E)	*SUVGly** (mmol/L)
	Mean±sd	95% CI	Abs var	IntraSV	InterSV
	(n = 12)	(relative value)	(%; )	(%; n = 6)	(%; n = 6)
	(n = 12)	(relative value)	(%; )	[EV, %]	[EV, %]
Thalamus	12.2±4.6	[2.1;22.4]	27.8±31.4	39.4 [100]	0.0
Globus pallidum	10.9±4.1	[1.9;19.8]	27.3±30.9	38.8 [100]	0.0
Caudate nucleus	13.3±4.6	[3.2;23.5]	27.0±31.0	36.8 [100]	0.0
Putamen	13.8±4.7	[3.5;24.2]	26.2±30.8	36.2 [100]	0.0
Cortex	10.9±3.5	[3.2;18.6]	24.9±29.1	33.8 [100]	0.0
Midbrain	11.7±4.2	[2.4;21.0]	26.9±30.7	38.2 [100]	0.0
Pons	9.6±3.1	[2.8;16.3]	24.1±29.2	33.8 [100]	0.0
Cerebellum	11.6±3.8	[3.2;20.0]	22.8±27.6	33.0 [100]	0.0
Frontal cortex	13.7±4.6	[3.5;23.8]	27.9±30.3	36.2 [100]	0.0
Occipital cortex	10.5±4.3	[1.0;19.9]	26.7±35.1	43.0 [100]	0.0

[.] refers to explained variance (EV). Estimates and absolute variability expressed as mean ± SD. InterSV = inter-subject variability; IntraSV = intra-subject variability.

Table 1. Mean, confidence interval, total, intra- and inter-subject variabilities of outcome parameters between [18F]FDG test and retest scans.

Table 1. Mean, confidence interval, total, intra- and inter-subject variabilities of outcome parameters between [¹⁸F]FDG test and retest scans.