Table 1.
Groups | Description | Injection Components | Number of Animals | 3D Intensity Footprints Achilles Functional Index (AFI) | Histological Analysis | Biomechanical Testing |
---|---|---|---|---|---|---|
ASCs+GMs | ASCs and GMs | ASCs (105)-loaded 120 GMs in 60 μL DMEM | 16 | 4b | 3c | 5 |
ASCs | Cell control | 106 ASCs in 60-μL DMEM | 16 | 4b | 3c | 5 |
GMs | GM control | 120 blank GMs in 60-μL DMEM | 16 | 4b | 3c | 5 |
Defect | Blank defecta | 60-μL DMEM | 16 | 4b | 3c | 5 |
Notes: aComplete transverse incisions was made 7 mm proximal to the calcaneal insertion with no surgical repair. bn = 4 picked at random from each experimental groups at 1, 4, 7, 10, 14, 21, and 28 days. cn = 3 sampled randomly from each experimental groups of eight animals at 2 weeks and 4 weeks with the remaining five samples used for biomechanical testing.