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. 2020 Oct 5;3(5):1589–1600. doi: 10.1016/j.matt.2020.09.021

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Assessment of Sampling Efficiency of MN/Ab Swabs on COVID-19 Models and Patients

(A) The rats were treated by the COVID-19 pseudovirus, which contains nuclear acid similar to that of SARS-CoV-2 but without high infection, followed by swab sampling and storage in VPS.

(B) The swabs were immersed in VPS within 24 h, followed by qRT-PCR testing.

(C) N gene, E gene, and ORF1ab gene were tested, indicating low Ct values for the MN/Ab group compared with others.

(D) The MN/Ab swab was applied to a patient, in similar manner to application of a regular swab.

(E) CT scanning verified the COVID-19-positive patient.

(F) Side-effect comparison between regular swabs, MN/swab, and MN/Ab swab.

(G) Comparison of absolute Ct value for three genes.

(H) Comparison of relative Ct value for three genes.