Table 2.

Effect of allocation to lopinavir–ritonavir on key study outcomes

		Lopinavir–ritonavir (n=1616)	Usual care (n=3424)	RR (95% CI)	p value
Primary outcome
28-day mortality		374 (23%)	767 (22%)	1·03 (0·91–1·17)	0·60
Secondary outcomes
Discharged from hospital within 28 days		1113 (69%)	2382 (70%)	0·98 (0·91–1·05)	0·53
Receipt of invasive mechanical ventilation or death*		449/1556 (29%)	871/3280 (27%)	1·09 (0·99–1·20)	0·092
	Invasive mechanical ventilation	152/1556 (10%)	279/3280 (9%)	1·15 (0·95–1·39)	0·15
	Death	350/1556 (22%)	712/3280 (22%)	1·04 (0·93–1·16)	0·54

Data are n (%) or n/N (%), unless otherwise indicated. RR=rate ratio for the outcomes of 28-day mortality and hospital discharge, and risk ratio for the outcome of receipt of invasive mechanical ventilation or death (and its subcomponents).

^*Analyses exclude those on invasive mechanical ventilation at randomisation.