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. 2020 Jun 16;295(40):13711–13723. doi: 10.1074/jbc.RA120.014183

Figure 10.

Figure 10.

DPP3 exerts a sex-specific effect on the knockout mice. A, body weight (A) and body composition of female mice (B) fed a regular chow diet. C and D, daily food intake (C) and water consumption (D) was measured in metabolic cages over the light and dark phases in DPP3−/− and DPP3+/+ female mice (12–16 weeks of age; n = 6/group) fed a regular chow diet over a period of 6 consecutive days. E, concentration of RAS peptides in serum measured by LC–MS in DPP3−/− and DPP3+/+ female mice (12–16 weeks of age; n = 8/group). F, quantification of ROS production in DPP3−/− and DPP3+/+ female mice (12–16 weeks of age; n = 5/group). *, p < 0.05; **, p < 0.01 versus WT mice based on unpaired two-sided Student's t test. The data represent means ± S.D.