Figure 2.

DPP3^−/− mice display lower body weight and altered food and water intake. A and B, body weight (A) and body composition (B) of male mice fed a regular chow diet. C–H, cumulative (top panels) and total (bottom panels) food intake (C and F, respectively), water consumption (D and G, respectively), and locomotive motion (E and H, respectively) were measured in metabolic cages over the light and dark phases in male DPP3^−/− and DPP3^+/+ mice (12–16 weeks of age; n = 6/group) fed a regular chow diet over a period of 6 consecutive days. *, p < 0.05; **, p < 0.01 versus WT mice based on unpaired two-sided Student's t test. The data are representative for two independent cohorts and presented as the means ± S.D.