DPP3 knockout renders mice susceptible to oxidative stress.
A–C, quantification of (ROS production (A), lipid peroxidation (B), and catalase activity (C) in kidney homogenates of male DPP3−/− and DPP3+/+ mice (12–16 weeks of age; n = 5/group). *, p < 0.05; **, p < 0.01 versus WT mice based on unpaired two-sided Student's t test. The experiments were performed in technical triplicates, and the data represent the means ± S.D.