Table 2.
Univariate and Multivariate Analyses of Prognostic Factors Associated with Overall Survival
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age (≥60 vs <60) | 1.11 (0.53–1.67) | 0.512 | ||
| Gender (male vs female) | 1.09 (0.54–1.86) | 0.345 | ||
| Tumor size (≥ 7 vs <7) | 1.43 (0.95–2.12) | 0.078 | ||
| Histological grade (G3-4 vs G1-2) | 2.25 (1.17–3.56) | 0.010* | 2.01 (0.89–3.23) | 0.089 |
| TNM stage (III-IV vs I-II) | 1.78 (1.34–2.13) | 0.001* | 1.71 (1.23–2.02) | 0.011* |
| Lymph nodes metastasis (positive vs negative) | 1.45 (0.78–2.87) | 0.098 | ||
| Vascular invasion (yes vs no) | 2.56 (1.78–3.13) | <0.001* | 2.12 (1.65–3.01) | 0.001* |
| miR-758-3p expression (high vs low) | 0.57 (0.48–0.93) | 0.001* | 0.53 (0.46–0.88) | 0.013* |
Note: *P <0.05.
Abbreviations: HR, hazard ratio; CI, confidence interval.