Table 3.
Univariate and Multivariate Analyses of Prognostic Factors Associated with Recurrence-Free Survival
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age (≥60 vs <60) | 1.13 (0.49–1.56) | 0.425 | ||
| Gender (male vs female) | 1.11 (0.64–1.93) | 0.278 | ||
| Tumor size (≥ 7 vs <7) | 1.33 (0.87–2.08) | 0.112 | ||
| Histological grade (G3-4 vs G1-2) | 2.11 (0.91–3.32) | 0.093 | ||
| TNM stage (III-IV vs I-II) | 1.98 (1.43–2.34) | <0.001* | 1.82 (1.31–2.13) | 0.001* |
| Lymph nodes metastasis (positive vs negative) | 1.56(0.68–2.98) | 0.113 | ||
| Vascular invasion (yes vs no) | 2.78 (1.69–3.24) | 0.001* | 2.12 (1.65–3.01) | 0.003* |
| miR-758-3p expression (high vs low) | 0.53 (0.41–0.79) | 0.002* | 0.57 (0.44–0.84) | 0.033* |
Note: *P <0.05.
Abbreviations: HR, hazard ratio; CI, confidence interval.