Table 1.
Baseline characteristics
| Cases |
All patients N=302 |
IST first-line N=226 |
Allo HCT first-line N=76 |
P-value |
|---|---|---|---|---|
| Age at diagnosis (years), median (IQR) | 24 (1-80) | 27 (14-54) | 18 (11-26) | < 0.001 |
| Sex (M/F) , n (%) | 161 (53) / 141 (47) | 123 (54) / 103 (46) | 37 (49) / 38 (51) | 0.444 |
| Etiology of AA, n (%) | 0.014 | |||
| Idiopathic | 233 (77) | 176 (78) | 57 (75) | |
| Congenital | 12 (4) | 4 (1) | 8 (11) | |
| Toxic | 16 (5) | 12 (5) | 4 (5) | |
| Drug-related | 19 (6) | 16 (7) | 3 (4) | |
| Infectious | 22 (7) | 18 (8) | 4 (5) | |
| Severity of AA, n (%) | 0.009 | |||
| VSAA | 79 (26) | 60 (27) | 19 (25) | |
| SAA | 142 (47) | 110 (49) | 32 (42) | |
| NSAA | 69 (23) | 52 (23) | 17 (22) | |
| Inherited | 12 (4) | 4 (2) | 8 (11) |