TABLE 6.
Genes involved in different abiotic stresses in the E. roggenkampii ED5 genome.
| Activity description | Gene name | Gene annotation | E.C. number | Chromosome location |
| Cold-shock protein | cspA | Cold-shock protein CspE | – | 1250628–1250837 |
| cspA | Cold shock-like protein CspF | – | 2524947–2525147 | |
| cspA | Cold shock-like protein CspC | – | 2829049–2829258 | |
| Heat shock proteins | smpB | SsrA-binding protein | – | 3578158–3578640 |
| hslR | Heat-shock protein Hsp15 | – | 4329724–4330125 | |
| ibpA | Heat-shock protein | – | 10924–11379 | |
| ibpB | Heat-shock protein IbpB | – | 11516–11944 | |
| hspQ | Heat-shock protein HspQ | – | 1617738–1618055 | |
| Heavy metal resistance | ||||
| Cobalt-zinc-cadmium resistance | czcD | Cobalt-zinc-cadmium efflux system protein | – | 1346027–1346959 |
| Magnesium transport | corA | Magnesium transporter CorA | – | 4489170–4490120 |
| corC | Magnesium and cobalt transporter | – | 1274635–1275558 | |
| cobA | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 2.5.1.17 | 2652149–2652739 | |
| Copper homeostasis | CopC | Copper resistance protein C | – | 2849097–2849468 |
| CopD | Copper resistance protein D | – | 2848226–2849095 | |
| cusA | Cu(I)/Ag(I) efflux system membrane protein CusA/SilA | – | 2326056–2329196 | |
| cusB | Membrane fusion protein, Cu(I)/Ag(I) efflux system | – | 2329207–2330454 | |
| cusF | Cu(I)/Ag(I) efflux system periplasmic protein CusF | – | 2330466–2330804 | |
| cusC | Outer membrane protein, Cu(I)/Ag(I) efflux system | – | 2330833–2332218 | |
| cusR | Two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR | – | 2332380–2333063 | |
| cusS | Two-component system, OmpR family, heavy metal sensor histidine kinase CusS | 2.7.13.3 | 2333053–2334507 | |
| copA | Cu+-exporting ATPase | 3.6.3.54 | 1099416–1101914 | |
| Zinc homeostasis | znuA | Zinc ABC transporter substrate-binding protein | – | 2864950–2865981 |
| znuC | Zinc ABC transporter ATP-binding protein ZnuC | 3.6.3. – | 2865972–2866727 | |
| znuB | Zinc ABC transporter permease | – | 2866724–2867509 | |
| – | Zinc/manganese transport system substrate-binding protein | – | 3653025–3653882 | |
| – | Zinc/manganese transport system ATP-binding protein | – | 3654781–3655434 | |
| zupT | Zinc transporter ZupT | – | 3987096–3987869 | |
| Zinc, cadmium, lead and mercury homeostasis | zntA | Zinc/cadmium/mercury/lead-transporting ATPase | 3.6.3.3 3.6.3.5 | 282265–284436 |
| Zinc homeostasis | adhP | Zinc-dependent alcohol dehydrogenase | 1.1.1.1 | 2407431–2408441 |
| htpX | Zinc metalloprotease HtpX | 3.4.24. | 2834324–2835202 | |
| zntB | Zinc transporter ZntB | – | 2581221–2582204 | |
| Manganese homeostasis | mntR | Transcriptional regulator MntR | – | 1415279–1415752 |
| mntH | Manganese transport protein | – | 3360108–3361283 | |
| – | Mn-containing catalase | – | 2257406–2258278 | |
| Drought resistance | nhaA | Na+:H+ antiporter, NhaA family | – | 683880–685010 |
| chaC | Cation transport protein ChaC | – | 2718487–2719182 | |
| chaB | Cation transport regulator | – | 2719360–2719590 | |
| chaA | Ca2+:H+ antiporter | – | 2719861–2720961 | |
| proB | Glutamate 5-kinase | 2.7.2.11 | 913547–914650 | |
| proA | Glutamate-5-semialdehyde dehydrogenase | 1.2.1.41 | 914662–915915 | |
| proQ | ProP effector | – | 2837467–2838153 | |
| proV | Glycine betaine/L-proline ABC transporter ATP-binding protein | 3.6.3.32 | 3632168–3633370 | |
| proW | Proline/betaine ABC transporter permease ProW | 3633363–3634427 | ||
| proX | Glycine betaine ABC transporter substrate-binding protein | 3634437–3635432 | ||
| proP | Proline/betaine transporter | 389805–391307 | ||
| proS | Proline–tRNA ligase | 6.1.1.15 | 865261–866979 | |
| betA | Choline dehydrogenase | 1.1.99.1 | 1187889–1189553 | |
| betB | Betaine-aldehyde dehydrogenase | 1.2.1.8 | 1189567–1191039 | |
| betT | Choline/glycine/proline betaine transport protein | – | 1191769–1193802 | |
| gabD | Succinate-semialdehyde dehydrogenase [NADP (+)] | 1.2.1.16 1.2.1.79 1.2.1.20 | 589996–591366 | |
| trkA | Trk system potassium transport protein TrkA | – | 4256588–4257964 | |
| trkH | Trk system potassium uptake protein | – | 4458220–4459671 | |
| trkH | Trk system potassium uptake protein | 3960701–3962176 | ||
| kup | Potassium transporter Kup | – | 4660743–4662611 | |
| kdpE | DNA-binding response regulator | 2.7.13.3 | 1302671–1303348 | |
| kdpD | Two-component sensor histidine kinase | 3.6.3.12 | 1303345–1306032 | |
| kdpC | Potassium-transporting ATPase subunit C | 3.6.3.12 | 1306033–1306608 | |
| kdpB | K+-transporting ATPase subunit B | 3.6.3.14 | 1306621–1308669 | |
| kdpA | Potassium-transporting ATPase subunit KdpA | – | 1308688–1310367 | |
| kdpF | K+-transporting ATPase subunit F | – | 1310367–1310570 | |