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. 2020 Oct 1;6(9):e04978. doi: 10.1016/j.heliyon.2020.e04978

Table 1.

Binding affinity and Percent of resemblance of all 5-FU analogues compared to standard 5-FU.

Candidate Binding affinity BEDSA Percentage of resemblance
5-FU -8.1 0 100%
PRA1 -8.6 0.5 88.89%
PRA2 -8.5 0.4 88.89%
PRA3 -8.2 0.1 66.67%
PRA4 -8.8 0.7 88.89%
PRA5 -8.8 0.7 88.89%
PRA6 -8.8 0.7 88.89%
PRA7 -8.4 0.3 88.89%
PRA8 -8.4 0.3 100.00%
PRA9 -8.8 0.7 88.89%
PRA10 -9.1 1 66.67%
PRA11 -7.7 -0.4 66.67%
PRA12 -8.4 0.3 66.67%
PRA13 -8.3 0.2 66.67%
PRA14 -8.9 0.8 88.89%
PRA15 -8.3 0.2 100.00%
PRA16 -8.1 0 66.67%