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. 2020 Oct 5;10:16501. doi: 10.1038/s41598-020-73552-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of CD300e in tissue macrophages. Immunohistochemical staining for CD300e (brown) and CD163 (blue) was performed on sections of normal colon mucosa, lung and liver. Arrows highlight macrophages which strongly express CD300e, while asterisks highlight weakly expressing macrophages. The percentage of CD163⁺ macrophages, CD300e^bright, CD300e^dim or not expressing CD300e, in 3 patients for colon mucosa and liver and in 4 patients for lung was calculated and expressed in the bottom plot as mean ± SEM. Original magnification 400× , inset magnification 600 × .