Table 2.
Descriptive Statistics for Phenotypes, Treatments, and Demographic Variables in SJLIFE and CCSS
| Phenotypes/Variables | Unit | SJLIFE n | SJLIFE % or Median (IQR) | CCSS n | CCSS % or Median (IQR) |
|---|---|---|---|---|---|
| Demographic Variables | |||||
| Sex | |||||
| Male | % | 2,231 | 53.0% | 4,513 | 48.1% |
| Female | % | 2,231 | 47.0% | 4,513 | 51.9% |
| Age | years | 2,231 | 35.8 (13.3) | 4,513 | 40.9 (12.9) |
| Treatments (any exposure) | |||||
| Radiation, any type | % | 2,231 | 58.3% | 4,513 | 61.9% |
| Chemotherapeutic agent, any type | % | 2,231 | 85.3% | 4,513 | 73.9% |
| Cranial radiation | % | 2,199 | 31.0% | 4,227 | 30.9% |
| Cardiac-directed radiation | % | 2,199 | 22.9% | 4,224 | 26.7% |
| Abdominal radiation | % | 2,199 | 20.0% | 4,226 | 25.9% |
| Pelvic radiation | % | 2,199 | 17.5% | 4,226 | 20.5% |
| Anthracyclines | % | 2,231 | 57.9% | 4,290 | 35.8% |
| Glucocorticoids | % | 2,231 | 47.8% | 4,513 | 43.4% |
| Platinums (cisplatin, carboplatin) | % | 2,227 | 10.3% | 4,513 | 4.4% |
| Phenotypes | |||||
| Anthropometric | |||||
| Height | cm | 2,025 | 168.7 (14.6) | 4,212 | 168.0 (18.0) |
| Body mass index | kg/m2 | 2,229 | 27.6 (9.3) | 4,208 | 26.1 (7.3) |
| Waist-to-hip ratio | ratio | 2,204 | 0.9 (0.1) | – | – |
| Blood Pressure | |||||
| Systolic blood pressure | mmHg | 2,020 | 123.0 (17.7) | – | – |
| Diastolic blood pressure | mmHg | 2,020 | 75.5 (13.0) | – | – |
| Serum Lipids | |||||
| High-density lipoprotein | mg/dL | 1,984 | 49.0 (20.0) | – | – |
| Low-density lipoprotein | mg/dL | 1,964 | 107.0 (46.0) | – | – |
| Total cholesterol | mg/dL | 1,997 | 183.0 (50.0) | – | – |
| Triglycerides | mg/dL | 1,997 | 100.0 (80.0) | – | – |
| Cardiometabolic Disease | |||||
| Coronary artery disease | % cases | 2,079 | 4.7% | 4,036 | 4.1% |
| Obesity | % cases | 2,229 | 38.3% | 4,208 | 25.8% |
| Type 2 diabetes | % cases | 2,112 | 7.1% | 4,207 | 7.0% |