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. 2020 Sep 21;107(4):714–726. doi: 10.1016/j.ajhg.2020.08.022

Figure 2.

Figure 2

Manhattan Plots of BGW-TWAS Results of AD Clinical Diagnosis and Global AD Pathology

Here, -log10(p values) by BGW-TWAS were plotted and red lines denote genome-wide significant threshold (2.5 × 10−6) for gene-based association studies. ZC3H12B was found to be significantly associated with both AD clinical diagnosis (A) and global AD pathology (B).