Table 1. Descriptive Statistics of the Cohort’s Demographics and Clinical Characteristics.
| Characteristic | No. (%) | P value of mean differencesa | ||
|---|---|---|---|---|
| Total cohort (N = 79 040) | No early NIT (n = 62 876) | Early NIT (n = 16 164) | ||
| Outcomes, within 30 d | ||||
| Acute MI or deathb | 344 (0.4) | 296 (0.5) | 48 (0.3) | .003 |
| Death | 143 (0.2) | 134 (0.2) | 9 (0.1) | <.001 |
| MI | 209 (0.3) | 170 (0.3) | 39 (0.2) | .52 |
| Coronary revascularization | 209 (0.3) | 143 (0.2) | 66 (0.4) | <.001 |
| MACE | 355 (0.4) | 306 (0.5) | 49 (0.3) | .002 |
| Demographics and clinical characteristics | ||||
| Age, mean (SD), y | 57.1 (16.3) | 55.7 (16.8) | 62.4 (12.6) | <.001 |
| ≥65 | 27 441 (34.7) | 20 221 (32.2) | 7220 (44.7) | <.001 |
| Female | 45 586 (57.7) | 36 782 (58.5) | 8804 (54.5) | <.001 |
| White | 40 787 (51.6) | 31 822 (50.6) | 8965 (55.5) | <.001 |
| Active/passive smoker | 5663 (7.2) | 4562 (7.3) | 1101 (6.8) | .051 |
| BMI, mean (SD), kg/m2 | 30.0 (6.88) | 30.0 (6.95) | 30.0 (6.60) | .83 |
| Overweight or obese | 60 191 (76.2) | 47 595 (75.7) | 12 596 (77.9) | <.001 |
| Elevated troponin (0.04-0.5) | 2854 (3.6) | 2085 (3.3) | 769 (4.8) | <.001 |
| CAD | 13 987 (17.7) | 10 877 (17.3) | 3110 (19.2) | <.001 |
| Stroke | 2006 (2.5) | 1595 (2.5) | 411 (2.5) | .97 |
| PTCA or CABG in prior year | 1008 (1.3) | 859 (1.4) | 149 (0.9) | <.001 |
| Family history | ||||
| CAD | 26 337 (33.3) | 20 526 (32.6) | 5811 (36) | <.001 |
| Stroke | 14 472 (18.3) | 11 507 (18.3) | 2965 (18.3) | .90 |
| Medications | ||||
| Antidiabetic | 12 493 (15.8) | 9423 (15) | 3070 (19) | <.001 |
| Antihyperlipidemia | 23 947 (30.3) | 17 880 (28.4) | 6067 (37.5) | <.001 |
| Antihypertension | 33 673 (42.6) | 25 580 (40.7) | 8093 (50.1) | <.001 |
| Anticoagulant | 7459 (9.4) | 5902 (9.4) | 1557 (9.6) | .49 |
| Elixhauser comorbidity index, mean (SD) | 3.6 (2.98) | 3.5 (3.04) | 3.7 (2.73) | <.001 |
Abbreviations: BMI, body mass index, calculated as weight in kilograms divided by height in meters squared; CABG, coronary artery bypass graft; CAD, coronary artery disease; MACE, major adverse cardiovascular event; MI, myocardial infarction; NIT, noninvasive cardiac testing; PTCA, percutaneous transluminal coronary angioplasty.
a
χ2 or analysis of variance tests.
b
A total of 8 patients had MI and died subsequently. They have not been counted twice in the composite outcome.