Table 1.

Enrichment Estimates for 24 Non-Cell-Type-Specific Functional Categories for EOC and HGSOC

Functional Category	All EOC		HGSOC
	Enrichment	p Value	Enrichment	p Value
3′ UTR	17.29	0.02	18.40	0.01
5′ UTR	−0.62	0.89	5.12	0.71
Coding	3.55	0.75	8.05	0.30
Conserved	24.94	0.06	21.82	0.07
CTCF	−9.62	0.11	−3.86	0.47
DGF	1.71	0.82	−0.92	0.52
DHS	3.42	0.35	0.50	0.83
Enhancer	2.66	0.69	2.56	0.71
FANTOM5 enhancer	−2.46	0.86	12.42	0.51
Fetal DHS	0.41	0.87	−1.52	0.50
H3K27Ac (Hnisz et al.36)	1.96	0.01	1.77	0.03
H3K27Ac (PGC2)	3.61	0.01	2.42	0.16
H3Kme1	2.02	0.16	1.82	0.28
H3Kme3	3.91	0.07	1.01	0.99
H3K9ac	3.25	0.33	0.90	0.96
Intron	1.46	0.12	1.24	0.35
Promoter	8.69	0.02	6.99	0.06
Promoter flanking	10.38	0.49	−2.90	0.76
Repressed	−0.32	0.07	0.67	0.64
Superenhancer	2.09	0.02	1.83	0.12
Transcription factor binding site	4.93	0.16	2.21	0.66
Transcribed	1.87	0.24	1.05	0.95
TSS	5.28	0.55	0.56	0.96
Weak enhancer	9.06	0.35	4.69	0.68

Enrichment was calculated as $\mathit{Pr}\left({\mathit{h}}_{\mathit{g}}^2\right)/\mathit{Pr}\left(\mathit{SNPs}\right)$, which shows the proportion of estimated SNP heritability explained by the proportion of SNPs in the functional category. Statistically significant associations (p values < 0.05) are marked in bold.