Figure 10.

Model of the role of AtOXR2 in plant defense. AtOXR2 is part of a loop for the activation of the SA-mediated plant defense pathway. By increasing ROS levels, AtOXR2 induces SA synthesis. In turn, SA, pathogens, and oxidative stress (ROS) stimulate the expression of AtOXR2. Increased AtOXR2 expression modifies the intracellular cytosolic redox environment, producing an increment in total GSH content and inducing the translocation of NPR1 to the nucleus, thus increasing defense and preparing plants against a potential pathogen attack. Black arrows correspond to connections known and established by other authors. Blue arrows represent results previously published by our group (Colombatti et al., 2019). Green-dotted arrows indicate original results presented in this work.