Figure 2.

Changes in fecal microbiota composition after butyrate supplementation or allogenic FMT. (A) Biplot of redundancy analysis (RDA axis 1 vs axis 2) of fecal microbiota data constrained by butyrate vs allogenic FMT treatment variables (before, baseline, and 4 weeks after treatment). Baseline fecal microbiota composition in the post-RYBG feces donors is also shown. (B) Biplot of deltas from the top 10 amplicon sequence variant (ASV) markers of fecal microbiota after allogenic FMT and butyrate treatment. AUC = 0.83 ± 0.29. (C) Spider plot depicting a panel of bacterial species that significantly differentiated between the 2 different treatment groups based on changes in the fecal microbiota composition. The axis reflects the amount of change in % of the bacterial species after either treatment.