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. 2020 Oct 5;8(1):e001372. doi: 10.1136/bmjdrc-2020-001372

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Comparison of serum and urine mitochondrial DNA (mtDNA) copy number at baseline. (A) Serum mitochondrial nicotinamide adenine dinucleotide dehydrogenase subunit-1 (mtND-1), (B) serum cytochrome-c oxidase 3 (COX-3), (C) urine mtND-1, (D) urine mitochondrial COX-3 (mtCOX-3) in healthy volunteers, patients with obesity and patients with obesity with type 2 diabetes mellitus (T2DM) group at baseline. Box represents first and third quartile and median. Statistical differences between groups were analyzed by analysis of variance followed by Fisher’s LSD test. LSD, least significant difference.