Fig. (1).

Sleep disorders and associated diseases linked to cancer risk. Obesity is a well-known condition associated with cancer. Obesity increases oxidative stress in the body and induces DNA damage. In turn, DNA damage may promote oncogenic processes. Insomnia is a complex condition that may result in depression of the immune system and is associated with impaired melatonin secretion and regulation of clock genes. Obstructive Sleep Apnea may cause intermittent hypoxia with the resulting alteration of adiponectin, a key antiproliferative factor. It is possible obesity, insomnia, and OSA increase the risk for the development of several types of cancer including, breast, prostate, thyroid, gastric, and lung cancer. (A higher resolution / colour version of this figure is available in the electronic copy of the article).