Figure 6.

Shared ancestry reveals potential locations of HMS modifiers. Contrasting patterns of subspecific ancestry among inbred strains that contribute to the observed phenotypes. Shared regions between PWK and DBA2 (green) may harbor alleles that rescue fertility in PWKDBA2 males. Regions shared between PWK, A/J, and B6 (blue) or regions shared privately between B6 and A/J (orange) may associate with age-dependent HMS. Private incompatibilities between PWK and 129S1 (red) may underlie the complete sterility of PWK129S1 males. Gray bars indicate the location of QTL identified in previous studies of HMS.